Advanced Clinicals

Advanced Clinicals Retinol Serum for Face, 1.75 fl oz — Nighttime Anti-Aging with Vitamin E & Green Tea for Smoother Texture

High-performance beauty made for confident daily results

$19.43

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Why customers choose Origin Beauty

Advanced Clinicals Retinol Serum for Face is a nighttime anti-aging serum formulated with retinol, green tea, and vitamin E to help visibly refine skin texture, hydration, and the appearance of fine lines.

This lightweight, milky serum combines stabilized retinol with antioxidant-rich green tea and nourishing vitamin E to support a smoother-looking complexion. Designed by Advanced Clinicals’ formulation team, the blend aims to deliver hydration and a refined surface feel while fitting into a simple evening routine. The product is made with dermatologist-tested methods and is recommended for gradual introduction if you are new to retinol.

How should I introduce this retinol serum into my skincare routine?

Start slowly to let your skin adapt: use the serum once per week during the first two weeks, then increase frequency every few weeks as tolerated. Apply on clean, dry skin at night and always follow with a broad-spectrum sunscreen during the day.

  • Patch-test before first use to check for sensitivity.
  • Begin with once weekly, gradually building to 2–3 nights per week or nightly if tolerated.
  • Apply a pea-sized amount to face and neck after cleansing; allow absorption before layering other products.
  • Avoid combining with Vitamin C in the same routine—use Vitamin C in the morning, retinol at night.

What results can I expect and when might I notice them?

Individual results vary, but users typically notice a smoother skin texture and improved hydration within a few weeks. Visible changes to fine lines and tone often appear gradually over several weeks to months with consistent nighttime use.

  • Immediate: lightweight, milky texture leaves skin feeling hydrated and less crepey.
  • Short term (2–6 weeks): improved surface smoothness and softer-feeling skin.
  • Longer term (6–12+ weeks): more refined appearance of lines and uneven texture when used consistently.
  • Use sunscreen daily to protect skin and support visible improvements.

What are the key ingredients and how do they support skin appearance?

The formulation pairs retinol with green tea extract and vitamin E to balance renewal with antioxidant support. Retinol helps support cellular turnover over time, while green tea and vitamin E help hydrate and provide antioxidant benefits for a calmer-looking complexion.

  • Retinol: supports surface renewal to help smooth texture (use gradually).
  • Green tea extract: antioxidant-rich, contributes to calmer-looking skin.
  • Vitamin E: helps nourish and deliver added moisturization.
  • Milky serum base: lightweight hydration that glides on and absorbs cleanly.

Are there any precautions or tips for sensitive skin?

Retinol can increase sensitivity, so take precautions if you have reactive or easily irritated skin. Always perform a patch test, introduce the product slowly, and avoid layering with other potential irritants until your skin adjusts.

  • Patch-test behind the ear or on the inner forearm before full-face use.
  • Reduce frequency or mix with your moisturizer if irritation occurs.
  • Skip use on sunburned, injured, or highly irritated skin.
  • Consult a skincare professional if you have specific concerns or conditions.

Who is this for? Advanced Clinicals Retinol Serum is suited for adults seeking to refine skin texture, add nightly hydration, and address the look of fine lines and uneven tone. It is appropriate for first-time retinol users who plan to introduce the ingredient gradually, as well as for experienced retinol users looking for a lightweight, antioxidant‑enriched nightly serum. Avoid during pregnancy or nursing and consult a healthcare provider with any medical concerns.

Ingredients

Aqua/Water/Eau, Isopropyl Myristate, Glycerin, Ethylhexyl Olivate, Cetearyl Alcohol, Pyrus Malus (Apple) Fruit Extract, Retinol, Phenoxyethanol, Avena Sativa (Oat) Bran Extract, Parfum/Fragrance, Ammonium Acryloyldimethyltaurate/VP Copolymer, Caprylyl Glycol, Oryza Sativa (Rice) Bran Extract, Ethylhexylglycerin, Hexylene Glycol, Cyamopsis Tetragonoloba (Guar) Gum, Citrus Aurantium Dulcis (Orange) Peel Extract, Copernicia Cerifera (Carnauba) Wax, Squalane, Polysorbate 20, Helianthus Annuus (Sunflower) Extract, Propanediol, Tetrasodium Glutamate Diacetate, Tocopherol, Rosmarinus Officinalis (Rosemary) Leaf Extract, 1,2-Hexanediol, Disodium Cocoamphodiacetate, Helianthus Annuus (Sunflower) Seed Oil, Camellia Sinensis Leaf Extract, Xanthan Gum, Ethyl Ferulate, Aloe Barbadensis Leaf Juice Powder, Humulus Lupulus (Hops) Extract, Limonene.

FAQ

Q: Can I use this retinol serum every night?

A: Start slowly—once weekly, then increase frequency as tolerated to 2–3 nights or nightly. Use sunscreen daily.

Q: Should I combine this with Vitamin C?

A: Avoid using Vitamin C and retinol at the same time; use Vitamin C in the morning and retinol at night.