Differin Acne Spot Treatment with 10% Benzoyl Peroxide

Differin 10% Benzoyl Peroxide Acne Spot Treatment is a maximum-strength, fast-acting pimple cream designed to target and reduce individual blemishes on the face and body.

This concentrated 1 oz spot treatment pairs 10% benzoyl peroxide—the highest over-the-counter concentration—with glycerin to address breakouts while helping to reduce surface dryness. It’s formulated for acne-prone skin and works where blemishes are visible: penetrating clogged pores, inhibiting acne-causing bacteria, and visibly reducing size and redness after the first application for many users. Use it as a targeted step within a broader skincare routine that includes cleansing, moisturizing, and sun protection.

How quickly will I see results on a pimple?

Many users notice reduced redness and a smaller-looking blemish after the first use, thanks to benzoyl peroxide’s antibacterial and pore-clearing action. Individual response varies by skin type and severity, but the formula is designed for rapid spot-targeting rather than gradual daily maintenance.

• 10% benzoyl peroxide to attack acne-causing bacteria quickly
• Visible reduction in redness and size reported after initial application
• Use directly on dried, cleansed skin for targeted effect

Will this dry out or irritate my skin?

Benzoyl peroxide can cause dryness, so Differin combines it with glycerin to help maintain skin moisture while treating blemishes. Start with a single nightly application and increase frequency only if your skin tolerates it to limit irritation.

• Glycerin included to help reduce excessive dryness
• Begin with once-daily use and monitor your skin’s response
• Apply moisturizer after treatment and always use SPF during daytime

How should I use this within my skincare routine?

Apply after cleansing and when your skin is completely dry to avoid excess absorption and irritation. Target the product only on affected areas, follow with a non-comedogenic moisturizer, and use sunscreen in daytime routines.

• Cleanse with a gentle face wash, pat skin dry
• Apply a thin layer directly on pimples and problem spots
• Follow with moisturizer; use SPF in the morning

Can it be used on body acne as well as the face?

Yes—this spot treatment is suitable for both facial and body blemishes where topical benzoyl peroxide is appropriate. Apply carefully to avoid over-application and protect clothing from bleaching, as benzoyl peroxide may discolor fabrics.

• Safe for targeted use on chest, back, and shoulders
• Avoid widespread application to large body areas to prevent irritation
• Keep away from hair and colored fabrics to prevent bleaching

Who is this for: Differin 10% Benzoyl Peroxide Acne Spot Treatment is for people with occasional to persistent spot breakouts who want a potent over-the-counter option to reduce blemish size and redness quickly. It’s intended for acne-prone skin that tolerates benzoyl peroxide; if you have very sensitive or severely inflamed skin, consult a dermatologist before starting a high-strength topical. Use as a targeted addition to a daily skincare plan that includes gentle cleansing, hydration, and sun protection.

Ingredients

Benzoyl Peroxide, Acrylates Copolymer, Carbomer, Diethylhexyl Sodium Sulfosuccinate, Disodium EDTA, Glycerin, Poloxamer 182, Propylene Glycol, Silica, Sodium Hydroxide, Water