Clinique Smart Clinical Repair Wrinkle-Correcting Face Serum, 1 fl oz — 9.5% Peptides & 1% Retinoid with Hyaluronic Acid

This concentrated 1 fl oz serum combines 9.5% peptides, 1% advanced retinoid and hyaluronic acid to target visible signs of aging from multiple angles. Developed by Clinique’s dermatology-led team, the formula aims to strengthen skin structure, accelerate surface renewal and provide immediate moisture to minimize the look of fine, dry lines. It’s fragrance-free, allergy-tested and formulated for use across skin types and tones.

How does this serum visibly reduce the look of wrinkles?

The serum uses a three-pronged approach: peptides to support skin strength, a retinoid to promote surface refinement, and hyaluronic acid to fill and hydrate. Together these act to improve texture, reduce the appearance of lines and create a smoother-looking complexion over time. Clinical testing has shown comparable improvements to a single laser treatment in overall wrinkle appearance after consistent use.

• 9.5% peptide complex to help reinforce skin resilience
• 1% advanced retinoid to accelerate cell turnover and refine texture
• Hyaluronic acid for immediate hydration and plumping effect
• Fragrance-free, allergy-tested formula suitable for sensitive skin

When and how should I add this serum to my skincare routine?

Apply the serum once or twice daily according to tolerance, typically after cleansing and before moisturizer. Start gradually if you’re new to retinoids—use every other night then increase—while always using daytime sun protection. Layering with hydrating products helps minimize dryness and supports comfort during initial adjustment.

• Use on clean, dry skin; a pea-sized amount covers face and neck
• Begin with alternate-night use, then progress to nightly as tolerated
• Follow with a moisturizer; use SPF during daytime when using retinoids
• Safe to include in both morning and evening routines if skin tolerates it

What results can I expect and how quickly?

Visible improvements depend on individual skin and consistency of use; many users notice smoother texture and reduced appearance of fine lines with continued application. Clinique’s clinical study reported comparable overall wrinkle improvement to a single microablative laser session after regular twice-daily serum use over several weeks. Hydration and temporary plumping effects are immediate, while structural benefits develop with ongoing use.

• Immediate: increased surface hydration and softer-feeling skin
• Weeks: refined skin texture and reduced visibility of fine lines
• With consistent use: improved overall wrinkle appearance and skin resilience
• Individual timelines vary by skin type and prior retinoid experience

Is this serum appropriate for sensitive or reactive skin?

Clinique formulated this serum to be allergy-tested and fragrance-free, and it is dermatologist-tested for tolerability. Because it contains an active retinoid, those with very reactive skin should introduce it slowly and monitor for irritation. Pairing with gentle cleansers and barrier-supporting moisturizers reduces risk of discomfort.

• Allergy tested and 100% fragrance-free for fewer irritants
• Dermatologist-tested and built for a wide range of skin types
• Introduce gradually if you have retinoid sensitivity
• Use barrier-repair moisturizers to mitigate dryness or flaking

Who is this for: Clinique Smart Clinical Repair Wrinkle Correcting Serum is designed for anyone seeking an advanced, science-driven solution to visible aging signs—those wanting smoother texture, fewer fine lines and improved hydration. It suits people who are comfortable introducing a retinoid into their regimen, including users with normal to sensitive skin who monitor tolerance and use sun protection during the day. Ideal for shoppers looking for clinically informed ingredients in a fragrance-free, dermatologist-backed formula.

Ingredients

Water\Aqua\Eau, Dimethicone, Isododecane, Butylene Glycol, Glycerin, Polysilicone-11, Ascorbyl Glucoside, Sodium Hyaluronate, Tocopheryl Acetate, Squalane, Hypnea Musciformis (Algae) Extract, Gelidiella Acerosa Extract, Sigesbeckia Orientalis (St. Paul's Wort) Extract, Helianthus Annuus (Sunflower) Seed Extract, Hordeum Vulgare (Barley) Extract\Extrait D'orge, Triticum Vulgare (Wheat) Germ Extract, Cucumis Sativus (Cucumber) Fruit Extract, Caffeine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Peg-10 Dimethicone, Glycyrrhetinic Acid, Whey Protein\Lactis Protein\Protéine Du Petit-Lait, Isohexadecane, Propylene Glycol Dicaprate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Acetyl Glucosamine, Cholesterol, Peg-8, Yeast Extract\Faex\Extrait De Levure, Peg-6, Dimethyl Isosorbide, Glyceryl Polymethacrylate, Polysorbate 20, Sodium Phosphate, Synthetic Fluorphlogopite, Polysorbate 80, Carbomer, Hexylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Potassium Hydroxide, Tin Oxide, Disodium Phosphate, Citric Acid, Disodium Edta, Sodium Citrate, Phenoxyethanol, Potassium Sorbate, Titanium Dioxide (Ci 77891) 49151 Please be aware that ingredient lists may change or vary from time to time. Please refer to the ingredient list on the product package you receive for the most up to date list of ingredients.