medicube Exosome Shot Zero Liquid Spicule Serum 1.01 fl.oz — 7,500 PPM Exosome Delivery, AHA+BHA+PHA for Pore Care & Texture

medicube Exosome Shot Zero 7,500 PPM is a liquid booster serum that uses micro spicules coated with patented exosomes to deliver actives directly into pores for improved texture, pore care, and hydration.

This lightweight ampoule combines exosome-coated spicules with AHA, BHA, and PHA acids and skin-supporting ingredients like niacinamide and panthenol to target dull texture, dead skin cells, and enlarged pores. Packaged as a 1.01 fl.oz treatment, the formula emphasizes absorption and targeted delivery rather than heavy occlusion, making it easy to layer into existing routines.

How does the spicule delivery help my skin feel smoother?

The micro needle-shaped spicules physically contact the skin surface to improve delivery of active ingredients where they are most needed. Because these spicules are coated with exosomes and actives, they assist deeper penetration and enhance ingredient uptake without aggressive abrasion.

• Exosome-coated spicules for focused delivery into pores
• Increased absorption rate versus applying ingredients alone
• Formulated to minimize irritation while supporting exfoliation

Will this serum help reduce visible pores and rough texture?

Yes—the blend of AHA, BHA, and PHA helps loosen and remove dead skin cells, while niacinamide supports a smoother-looking surface and more even texture. The exosome system targets delivery to pore walls, helping active ingredients reach areas that typical topical serums may miss.

• AHA/BHA/PHA combination for gentle chemical exfoliation
• Niacinamide to improve tone and refine skin appearance
• Exosome technology focused on pore-targeted action

Is this product suitable for sensitive or acne-prone skin?

medicube designed the formula to be low-irritating and non-comedogenic, and it is free from artificial colors and gluten. Still, because the product contains acids and physical spicules, patch testing is recommended and gradual introduction into a routine helps monitor tolerance.

• Clinically tested to be low-irritating and non-comedogenic
• Free of artificial colorants and gluten
• Start with a patch test and use sparingly if you have high sensitivity

How do I incorporate the Exosome Shot Zero into my skincare routine?

Use the ampoule after cleansing and any water-based essences, then follow with a light moisturizer to seal in benefits. medicube also recommends pairing the ampoule with their Collagen Jelly Cream or using it after targeted booster devices for enhanced results.

• Cleanse and tone, then apply the ampoule to affected areas
• Layer a water-based moisturizer afterward to lock in hydration
• Use 2–3 times per week initially, increasing frequency as tolerated

Who is this for: The medicube Exosome Shot Zero 7,500 PPM is designed for people wanting a next-generation targeted booster to address uneven texture, visible pores, and surface buildup. It suits those comfortable introducing mild acids and novel delivery systems into their routine—especially users seeking lightweight, fast-absorbing treatments that can be combined with existing serums and moisturizers. If you have very reactive skin or are on acne prescriptions, consult a dermatologist first and begin with a patch test to confirm compatibility.

Ingredients

Water,Dipropylene Glycol,Glycerin,Butylene Glycol,1,2-Hexanediol, Niacinamide,Sodium Polyacrylate,Ethylhexyl Palmitate,Hydrolyzed Sponge,C12-14 Alketh-12,Hydroge- nated Polydecene,Ethylhexylglycerin,Adenosine,Caprylyl/Capryl Glucoside,Disodium EDTA,Panthenol,Calcium Silicate,Lactobacillus Extracellular Vesicles,Campsis Grandiflora Flower Extract,Pueraria Lobata Root Extract,Pinus Palustris Leaf Extract,Oenothera Biennis (Evening Primrose) Flower Extract,Ulmus Davidiana Root Extract,Sodium Silicate,Betaine Salicylate,Citric Acid,Gluconolactone