Nioxin Scalp + Hair Thickening System 2 Shampoo — 10.1 fl oz for Natural/Untreated Hair, Niacinamide & Biotin

Nioxin Scalp + Hair Thickening System 2 Shampoo is a professional-grade cleanser formulated to remove buildup and help hair appear thicker and fuller for natural, untreated hair with progressed thinning.

Designed as the first step of Nioxin’s three-part System 2 regimen, this Derma-Purifying Shampoo uses Activ-Renewal technology to clear excess sebum, environmental residues, and fatty acids from the scalp and hair. The formula—enriched with niacinamide and biotin—prepares the scalp to receive the conditioner and leave-in treatment that follow, helping amplify hair structure and improve manageability. Clinically and dermatologically tested, the product targets the specific needs of natural hair experiencing advanced thinning without harsh stripping.

How does this shampoo help hair look thicker on a daily basis?

The shampoo clears pore-clogging oils and impurities that weigh hair down and reduce visual density. By improving the scalp environment and strengthening strand structure, the hair appears fuller and moves with more body after regular use.

• Activ-Renewal technology removes sebum and environmental residue
• Niacinamide supports scalp conditioning and visible texture improvement
• Biotin helps reinforce hair resilience to reduce breakage and thinning appearance
• Gentle cleansing preserves natural hair texture for daily use

Why is this shampoo suited for natural or untreated hair with progressed thinning?

System 2 is formulated specifically for natural hair that has experienced more pronounced thinning; it balances deep cleansing with conditioning support so the hair is not overstressed. The product prioritizes scalp health and structural support rather than chemical treatments, making it appropriate for untreated hair types.

• Designed for progressed thinning—targets visible density and fullness
• Non-aggressive cleansing that keeps natural hair integrity
• Complements Nioxin System 2 Conditioner and Scalp & Hair Treatment for best outcomes

How should I use this shampoo for best results?

Wet hair thoroughly, apply shampoo, and gently massage into the scalp and hair for about one minute before rinsing. Use daily as the first step in the three-part System 2 routine—follow with the Scalp Therapy Conditioner and the Scalp & Hair Treatment for a complete regimen.

• Apply to wet hair and lather for one minute to activate the formula
• Rinse thoroughly and follow with System 2 conditioner
• Use daily and pair with the leave-in treatment for consistent improvement

What results can I expect and in what timeframe?

Users report improved hair fullness and density with continued use; visible changes are commonly noticed within about 30 days when following the full System 2 regimen. The shampoo supports measurable improvements in hair feel and scalp condition without making therapeutic promises.

• Clinically tested for thicker-looking hair in routine use
• Reported consumer outcomes include increased fullness and density
• Best results when combined with conditioner and topical treatment

Who is this for: Nioxin System 2 Shampoo is intended for people with natural or untreated hair who are experiencing progressed thinning and want a salon-quality, scalp-focused cleansing step that prepares hair for targeted thickening treatments. It’s a practical daily option for anyone prioritizing scalp health and fuller-looking hair without altering their hair chemically.

Ingredients

Water/Eau, Sodium Laureth Sulfate, Sodium Lauryl Sulfate, Cocamidopropyl Betaine, Sodium Citrate, Sodium Xylenesulfonate, Sodium Chloride, Cocamide MEA, Sodium Benzoate, Citric Acid, Salicylic Acid, Mentha Piperita (Peppermint) Oil, Mentha Arvensis Leaf Oil, Menthol, Tetrasodium EDTA, Sodium Hydroxide, Methylparaben, Propylene Glycol, Camellia Sinensis Leaf Extract, Cystine Bis-PG-Propyl Silanetriol, Biotin, Lecithin, Niacinamide, Panthenol, Tocopheryl Acetate, Citrus Paradisi (Grapefruit) Peel Extract, Humulus Lupulus (Hops) Flower Extract, Urtica Dioica (Nettle) Leaf Extract, Yellow 5, Yeast Extract, Acer Saccharum (Sugar Maple) Extract, Citrus Limon (Lemon) Peel Extract, Saccharum Officinarum Extract, Vaccinium Myrtillus Leaf Extract, Blue 1, Citrus Aurantium Dulcis (Orange) Fruit Extract, Red 33, Potassium Sorbate.