NIOXIN System 2 Scalp + Hair Thickening Shampoo 16.9 fl oz — for Natural/Untreated Hair, Niacinamide & Biotin

NIOXIN System 2 Scalp + Hair Thickening Shampoo is a salon-grade cleanser formulated to remove buildup and visibly improve hair thickness and fullness for natural, untreated hair with progressed thinning.

Designed as the first step in NIOXIN’s three-part regimen, this 16.9 fl oz shampoo uses Activ-Renewal technology to strip sebum, environmental residues and fatty acids from the scalp and hair shaft so follow-up products can work more effectively. Clinically and dermatologically tested, System 2 aims to fortify fragile strands and give the appearance of denser hair with regular use. It pairs best with the matching System 2 Conditioner and Scalp & Hair Treatment to support overall scalp health and amplify hair structure.

How does this shampoo help hair that’s thinning naturally?

NIOXIN System 2 focuses on cleansing and fortifying: a deep clean reduces pore-clogging buildup and the formula includes key nutrients to improve hair resilience and manageability. Over time, hair looks fuller as breakage is minimized and each strand appears stronger.

• Activ-Renewal technology removes sebum and environmental residue
• Derma-purifying action targets scalp impurities
• Added niacinamide and biotin support healthier-looking strands
• Clinically tested for visible improvement in thickness and fullness

What results can I expect and when will I notice them?

Users typically report visible differences within about 30 days when using the full three-part System 2 routine daily. Expect improved scalp cleanliness immediately and gradual improvements in hair density, fullness and reduced breakage with consistent use.

• Immediate: cleaner scalp and less oily buildup
• 30 days: noticeable increase in hair density and fullness for many users
• Ongoing: reduced hair breakage and stronger-feeling strands
• Best results when combined with System 2 Conditioner and treatment

How should I use NIOXIN System 2 Shampoo for best effect?

Apply to wet hair, massage into the scalp and hair to create a lather for approximately one minute, then rinse thoroughly. Use daily as the first step in the three-part System 2 routine and follow with the Scalp Therapy Conditioner and Scalp & Hair Treatment for optimal results.

• Wet hair thoroughly before applying shampoo
• Massage into scalp for at least one minute to lift oils and debris
• Rinse completely to leave a clean base for conditioner and treatment
• Use daily and pair with full System 2 regimen for best outcome

Is this product suitable for my hair type and concerns?

System 2 is formulated specifically for natural, untreated hair experiencing progressed thinning. It’s targeted for people who want a professional-strength cleansing step that prepares the scalp and hair for thickening treatments without harsh stripping.

• Ideal for natural or untreated hair with progressed thinning
• Not intended for chemically treated or colored hair concerns
• Recommended as part of a three-step regimen for visible results
• Backed by salon experience and dermatological testing

Who is this for: NIOXIN System 2 Shampoo is best suited to people seeking a salon-quality scalp cleanser to address progressed thinning on natural, untreated hair. If you want a deep-cleansing first step that removes excess oils and environmental build-up while supporting thicker, fuller-looking hair when used consistently with the System 2 conditioner and treatment, this shampoo is formulated for that purpose. For chemically processed or color-treated hair, consider choosing the NIOXIN system designed for those specific needs.

• Size: 16.9 fl oz professional bottle for regular home use
• Awards: recognized by stylists for thinning hair care
• Ingredients of note: niacinamide, biotin, botanicals and antioxidants

Ingredients

Aqua, Sodium Laureth Sulfate, Sodium Lauryl Sulfate, Cocamidopropyl Betaine, Sodium Citrate, Sodium Xylenesulfonate, Sodium Chloride, Cocamide MEA, Sodium Benzoate, Citric Acid, Salicylic Acid, Mentha Piperita Oil, Mentha Arvensis Leaf Oil, Menthol, Tetrasodium EDTA, Sodium Hydroxide, Methylparaben, Propylene Glycol, Camellia Sinensis Leaf Extract, Cystine Bis-PG-Propyl Silanetriol, Biotin, Lecithin, Niacinamide, Panthenol, Tocopheryl Acetate, Citrus Paradisi Peel Extract, Humulus Lupulus Flower Extract, Urtica Dioica Leaf Extract, CI 19140, Faex Extract, Acer Saccharum Extract, Citrus Limon Peel Extract, Saccharum Officinarum Extract, Vaccinium Myrtillus Leaf Extract, CI 42090, Citrus Aurantium Dulcis Fruit Extract, CI 17200, Potassium Sorbate