Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream — Refillable Moisturizer, 21 Peptides for Hydration & Firmer Skin

This lightweight but deeply moisturizing cream combines 21 amplified peptides and neuropeptides with supportive ingredients like squalane, hyaluronic acid and cactus flower extract to plump skin and reduce the visible appearance of fine lines and expression wrinkles. Its formula targets multiple signs of aging—loss of bounce, diminished elasticity, texture irregularities and dehydration—while offering a refillable design to reduce waste. Results reported in a consumer perception study show visible improvement in several types of expression lines within one week for many participants.

How does this moisturizer improve the look of expression lines?

The cream uses a concentrated peptide complex — 21 amplified peptides and neuropeptides — to help smooth and visibly reduce the appearance of lines caused by facial movement. These act alongside hydrating agents to plump skin so lines look softer and less pronounced.

• 21 amplified peptides and neuropeptides to target expression lines
• Hyaluronic acid and trehalose for immediate hydration and plumping
• Lightweight texture helps active ingredients sit smoothly on skin

Will it hydrate dry skin without feeling greasy?

Yes — the formulation balances rich moisturizers with a weightless finish so skin feels nourished but not heavy. Squalane and cactus flower extract replenish lipids and lock in moisture while the cream sinks in quickly for comfortable wear under makeup or SPF.

• Squalane restores skin’s natural lipids and prevents moisture loss
• Cactus flower and trehalose provide lasting hydration in dry environments
• Non-greasy, fast-absorbing texture suitable for daily use

What skin concerns does it target besides lines and dryness?

Beyond expression lines and dehydration, the formula includes ingredients aimed at improving elasticity, radiance and overall texture. Gamma proteins and supportive hydrators contribute to a smoother-looking surface and more even tone over time.

• Gamma proteins to help with elasticity and bounce
• Hyaluronic acid and trehalose for surface smoothness and resilience
• Formulated to help skin appear brighter and more even with regular use

How does the refillable design work and why choose it?

The product is offered in a refillable format to reduce packaging waste and keep the premium dispenser reusable. Purchasing refill cartridges lets you maintain the original jar or pump while replacing only the inner product container.

• Refill cartridges compatible with the main moisturizer container
• Reduces single-use plastic by reusing outer packaging
• Convenient for regular users who want sustainable options

Who is this for: This moisturizer is suited for adults seeking a potent peptide-based treatment that combines visible line-smoothing with intense hydration. It works well for dry to combination skin types concerned about loss of firmness, fine lines, uneven texture or dullness and for anyone who prefers a refillable, lower-waste skincare choice. Avoid if you have known sensitivities to any listed ingredients; patch-test when trying a new active-rich product.

Ingredients

Water/Aqua/Eau, Glycerin, Dimethicone, Olive Oil Decyl Esters, Glycereth-26, Squalane, Butylene Glycol, Behenyl Alcohol, Polysilicone-11, Batyl Alcohol, Cetyl Alcohol, Simmondsia Chinensis (Jojoba) Seed Oil, Hexapeptide-11, Acetyl Hexapeptide-1, Tripeptide-10 Citrulline, Palmitoyl Dipeptide-10, Palmitoyl Hexapeptide-12, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Palmitoyl Tetrapeptide-7, Tripeptide-1, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Cereus Grandiflorus (Cactus) Flower Extract, Squalene, Phytosterols, Trehalose, Silanetriol Trehalose Ether, Biotin, Citric Acid, Lecithin, Sodium Lactate, Hydrogenated Lecithin, Caprylyl Glycol, Sorbic Acid, Mannitol, Amidinobenzyl Benzylsulfonyl D-Seryl Homophenylalaninamide Acetate, Potassium Sorbate, Sodium Benzoate, Glyceryl Stearate, Caprylic/Capric Triglyceride, Leuconostoc/Radish Root Ferment Filtrate, Sodium Hydroxide, Dimethyl Isosorbide, Potassium Hydrolyzed Polygamma-Glutamate, Laureth-12, Laureth-3, Dextran, Tocopherol, Hydroxyethylcellulose, Disodium Phosphate, Sodium Polyglutamate, Ethylhexylglycerin, Sodium Stearoyl Glutamate, Polyglyceryl-10 Myristate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 20, Carbomer, Triethanolamine, Sodium Phosphate, Acrylates Copolymer, Mica, Stearyl Alcohol, Phenoxyethanol.