Peter Thomas Roth Peptide Skinjection Wrinkle-Fix Serum - Amplified Refillable, High-Concentration Peptides

Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Serum is a clinically proven, refillable peptide serum designed to reduce the appearance of expression lines and help firm skin without needles. This lightweight, dual-purpose serum combines targeted peptide actives with a refillable delivery system. It can be used as a non-invasive alternative to injectable treatments or alongside professional procedures to extend visible results. The formula concentrates multiple peptide technologies—Matrixyl Morphomics, Argireline Amplified, Matrixyl Synthe’6 and Argirelox™—to target expression lines, support skin structure, and help improve the look of firmness over time.

How quickly will I notice changes in expression lines?

Visible improvements depend on individual skin and consistent use. Clinical data supporting Argirelox™ shows prolonged benefits when applied twice daily after neurotoxin treatment, and many users report smoother-looking lines within weeks of regular application.

• Use twice daily for best results.
• Contains high-concentration peptide complexes for targeted action.
• Results are gradual and cumulative—keep a steady routine.

Can this serum replace injectable treatments?

This product offers a needle-free approach to reduce the look of expression lines and can complement in-office injectables. It is formulated to help prolong the interval between professional treatments, though individual outcomes vary.

• Designed as non-invasive or complementary to injectables.
• Formulated with 10% Argirelox™ shown to extend benefits in a small clinical study.
• Safe for daily at-home use across all skin types.

What are the key peptides and why do they matter?

The serum blends several peptide technologies at notable concentrations to address multiple signs of aging. Matrixyl variants support visible firmness and structural appearance while Argireline forms help target expression-related movements.

• 2% Matrixyl Morphomics for structural peptide support.
• 5% Argireline Amplified to target expression line appearance.
• 2% Matrixyl Synthe’6 plus 10% Argirelox™ to help prolong visible improvements.

How does the refillable system work and why is it useful?

The serum comes in a reusable dispenser with replaceable refills, minimizing waste and ensuring a consistent pump experience. Refills snap into place so you can replenish the active formula without replacing the entire bottle.

• Refill pods reduce single-use plastic waste.
• Stable pump delivery preserves active potency and hygiene.
• Easy-to-replace cartridges keep daily routine simple.

Who is this for: This treatment is for people seeking a potent peptide serum to address expression lines, support the look of firmness, and reduce reliance on frequent in-office injections. It suits all skin types and is appropriate for anyone who wants an advanced at-home anti-aging step—whether as a standalone regimen or to extend results after professional cosmetic procedures. Use consistently as directed and pair with a broad-spectrum sunscreen during the day to protect results and skin health.

Ingredients

Water/Aqua/Eau, Dimethicone, Squalane, Butylene Glycol, Glycerin, Saccharomyces Lysate, Polysilicone-11, Acetyl Hexapeptide-8, Pentapeptide-18, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Palmitoyl Tripeptide-38, Collagen, Sodium Hyaluronate, Tocopherol, Phytosterols, Hydrogenated Lecithin, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid, Caprylic/Capric Triglyceride, Polyglyceryl-10 Myristate, Pentylene Glycol, Caprylyl Glycol, Sodium Benzoate, Sodium Phytate, Sodium Hydroxide, Potassium Sorbate, Ethylhexyl Palmitate, Hydroxypropyl Cyclodextrin Trihydroxystearin, Lauroyl Lysine, Glucomannan, Ethylhexylglycerin, Ammonium Acryloyldimethyltaurate/VP Copolymercarbomer, Glyceryl Stearate, Stearyl Alcohol, Behenyl Alcohol, Mica, Phenoxyethanol.

FAQ

Q: How often should I apply the Peptide Skinjection serum?

A: Apply twice daily, morning and evening, for best and consistent visible results.

Q: Is this serum safe to use with injectables?

A: Yes—it's designed to complement in-office treatments and may help extend visible results.